Non-disclosure preimplantation genetic diagnosis for Huntington's disease: practical and ethical dilemmas

1998 ◽  
Vol 18 (13) ◽  
pp. 1422-1426 ◽  
Author(s):  
Peter R. Braude ◽  
Guido M. W. R. de Wert ◽  
Gerry Evers-Kiebooms ◽  
Rachel A. Pettigrew ◽  
Joep P. M. Geraedts
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Preimplantation Genetic Diagnosis ◽  
Ethical Dilemmas ◽  
Genetic Diagnosis

scholarly journals Preimplantation genetic diagnosis for Huntington's disease with exclusion testing

2002 ◽  
Vol 10 (10) ◽  
pp. 591-598 ◽  
Author(s):  
Karen Sermon ◽  
Martine De Rijcke ◽  
Willy Lissens ◽  
Anick De Vos ◽  
Peter Platteau ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Preimplantation Genetic Diagnosis ◽  
Genetic Diagnosis

scholarly journals Preimplantation genetic diagnosis (PGD) for Huntington's disease: the experience of three European centres

2011 ◽  
Vol 20 (4) ◽  
pp. 368-375 ◽  
Author(s):  
Maartje C Van Rij ◽  
◽  
Marjan De Rademaeker ◽  
Céline Moutou ◽  
Jos CFM Dreesen ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Preimplantation Genetic Diagnosis ◽  
Genetic Diagnosis

scholarly journals Prenatal and Preimplantation Genetic Diagnosis of Huntington's Disease

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Joep P.M. Geraedts ◽  
Keyword(s):  
At Risk ◽  
Genetic Testing ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Preimplantation Genetic Diagnosis ◽  
Genetic Diagnosis ◽  
Preimplantation Genetic Testing ◽  
Dominant Disease ◽  
Pros And Cons ◽  
Disease Free

Huntington’s disease (HD) is an autosomal dominant disease that immensely impacts the affected families. However, the transmission of the disease from carriers to their offspring could be prevented. Prenatal diagnosis (PND) and preimplantation genetic diagnosis (PGD) are the only two available reproductive options for the carriers at risk to have disease-free children. PND for HD could be done through two kinds of genetic testing: direct and indirect. The same approaches are available for preimplantation genetic testing. In addition, a third alternative is nondisclosure testing, which is only available in the case of PGD. The pros and cons of different approaches are discussed. However, only a relatively few at-risk parents opt for PND and PGD. Furthermore, compared to PND, PGD is even more seldom opted for as a reproductive option.

scholarly journals Erratum: Preimplantation genetic diagnosis (PGD) for Huntington’s disease: the experience of three European centres

2012 ◽  
Vol 20 (9) ◽  
pp. 1010-1010 ◽  
Author(s):  
Maartje C Van Rij ◽  
◽  
Marjan De Rademaeker ◽  
Céline Moutou ◽  
Jos C F M Dreesen ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Preimplantation Genetic Diagnosis ◽  
Genetic Diagnosis
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